Demonic malware (timed debuffs; temporarily disable certain Praetor Suit functions)
* Worms (acquired by close proximity to infected machinery/enemies)
* Corrupt robotic assets (UAC robots or supply drones) the Slayer encounters
* Jam automap
* Jam HUD
* Viruses (require physical interaction with infected machinery/enemies)
* Disable ammo fabricators
* Disable armor fabricators
* Disable equipment items/tools
* Disable Harmonic Resonators (set heavy metal volume to 0)
* Disable power-ups
Mars (UAC)
* Ammo crates (restore all of Slayer's common ammo)
* Arena portals
* ATLAS shield batteries (powerful explosive/electric)
* Breakable walls/doors
* Coolant tanks (freeze enemies, briefly slow Slayer)
* Destructible platforms (usually over lava or nukage)
* Explosive barrels (presumed to contain Argent, damage Slayer and demons)
* Exposed wiring (can be shot to produce electric surge)
* Flame vents (from broken gas pipes; can be continuous or periodic)
* Gressen generators (gravity field generators; enable Earth-like gravity inside Mars Base)
* Health Station
* Industrial capacitors (electric barrels; do no damage but electrify enemies)
* Jump pads (malfunctioning gravity panels or DynoPhasic gravity elevators)
* Laser gates/grids
* Map stations
* Molten metal (harms both demons and the Slayer)
* Nuclear bombshell (tactical nukes, serve as "nuclear" explosive barrels)
* Nukage (corrosive/radioactive liquid waste; harmful to demons but harmless to the Slayer)
* Nukage barrels
* Plasma emitters (emit damaging surge across small area; can be mounted on floor or walls; can be continuous or periodic)
* Quick-deploy droid stations
* Psionic emitters (can be hijacked via relay terminals; can be used both by Slayer and Rambler Griefers to transmit psionic frequencies to distress opponents)
* Reinforced walls (in Lazarus Labs; highly resistant to damage; restrict the Slayer but not phase-shift-capable enemies)
* Security turrets (machine guns that deploy from ceiling to prevent unauthorized access)
* Teleporters
* Test-firing rocket engines (in Spaceport only)
Mars (natural)
* Dust storms (reduce visibility; boost electric attacks and raise chance of lightning strikes)
* Low gravity outside of Base
* Lightning strikes (damage and hitstun)
* Sand (shoot to raise obscuring dust plume)
Mars (demonic)
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* Backdoor (construct in shape of door, injects demonic malware when interacted with)
* Blackout Drone (produces cloud of metallic particles that obscures all light/sound in room; doesn't affect Clearsight)
* Blood Drone (corrupt supply drone; restores ammo but at cost of HEALTH)
* Cloak Drone (conceals single demon in cloaking field)
* CRTerror (fills area with rising audiovisual static; explode when destroyed)
* Cursed darkness (seen in Lazarus Labs - greatly reduces ambient light)
* Cyber Nest (cyborg Gore Nest; injects malware virus when destroyed)
* Demonic malware
* Dust Devils
* Evil Eyes (drains life and fills vision with hellish symbols when in their line-of-sight)
* Fireblu Torches (blind whenever in own field-of-view)
* Gore Nest
* Hellgrowth
* Portal Drone (follows Slayer and constantly transports demons closer to him)
* Suicide Drone (corrupt supply drone; explodes when interacted with for damage)
* Trojan Drone (corrupt supply drone; injects demonic malware when interacted with)
* Virus Drone (corrupt supply drone; kamikazes Slayer when sighted to explode and deliver demonic malware)
Hell (natural)
* Acid lakes (replace nukage)
* Blood Storm (highly corrosive metallic rains)
* Breakable floor over chasms/lava/spikes (shoot to break and drop demons)
* Collapsible stone columns (topple by Rampaging into them, crushing demons they fall onto)
* Crystal obelisks (topple by shooting at base, crushing demons they fall onto)
* Crystal spikes (impale enemies thrown onto them)
* Gas vents (lift/jump pads)
* Firestorm (incendiary storm)
* Lava lakes/rivers/falls (harms both demons and the Slayer)
* Shockspires (floating rock spikes energized with red electricity; hit with stun bomb to short out and release strong shockwave)
* Stalactites (topple by shooting at base, crushing demons they fall onto)
* Tyrant Star (damages whenever are caught in its scorching rays; must take cover within shadows)
Hell (artificial)
* Crusher ceilings/pillars
* Hellstorm Pylon (perimeter cannons defending Hell fortresses)
* Hive Nexus (demonic map station)
* Sentinel Bonfires (resting place of fallen Sentinel warriors, laid to rest by Slayer; restore Slayer's health)