2099: The techno-empire of Yapan rises from the ashes of old nation-states, its crown jewel a sprawling megalopolis known as Runner City. This neon-drenched maze of skyscrapers and underground warrens pulses with the fevered dreams of corrupt megacorporations and gutter-dwelling gangs alike. At the heart of this chrome beast, Zatrice - a child of the streets orphaned by the city's relentless appetite for blood - begins his ascent through layers of society and circuitry, his sole driving force: securing a better life for his younger sister, buella, trapped in the depths of a corpo-run plans